The latest data from Meta Platforms, Inc. shows a slight decline in the company's average daily active users for the quarter.

On Wednesday, April 29, at the close of trading in New York, S&P 500 futures fell by 0.39%, Dow futures declined by 0.98%, and Nasdaq 100 futures dropped by 0.06%.

On Wednesday (April 29), at the close of trading in New York, spot gold fell by 1.15% to $4,544.05 per ounce, continuing its overall downward trend. It traded within the range of $4,610.29-$4,510.32, hitting a daily low at the beginning of the U.S. stock session. During the Federal Reserve's resolution statement release and Jerome Powell's press conference, trading hovered near $4,540.

The Nasdaq Biotechnology Index closed down more than 1.2%. Among its constituent stocks, Tango Therapeutics fell by 12.25%, Personalis dropped 8.36%, PTC Therapeutics decreased by 8.13%, Foghorn slid 8.12%, and Erasca declined 7.98%.

The Nasdaq Golden Dragon China Index closed down 0.64% at 6791.66 points, showing an overall long-tail L-shaped trend.